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My father has blood group O-ve and my mother has blood group B+ve. I'm having blood group A+ve. Why is it so ?

The RHD gene makes the RHD protein. We don't know what this protein does but it sits on the outside of our red blood cells. And we know we can live without it because some people do not make any RHD protein.

These people are Rh-. The RHD+ (or "+") version of the gene contains a complete set of the instructions to make the RHD protein. RHD- (or "-") versions are either missing some of the instructions or have them scrambled up.

So Rh- people make no RHD protein because both versions of their RHD gene don't work. As you might have guessed, Rh+ people need just one working RHD gene.

This is because people with just one working copy of the RHD gene make enough RHD protein to be Rh+. But they still have an RH- version they can pass on to their kids. Like nearly everyone else, you have two copies of RHD -- one from your mom and one from your dad. So, to end up Rh-, BOTH of your Rh+ parents have to be CARRIERS for the Rh- version of the RH gene. They had one copy of the RH+ version and one copy of the RH- version.both sets of your grandparents most likely had to have at least one 'scrambled' version of the RHD gene. In other words, at least one grandparent from dad's side of the family was a carrier. And one from mom's side too.

This is the easiest and by far the most common way for your parents to have each inherited an RHD- gene.May be this is the reason.


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