Ask a Teacher
WHAT IS THE ADVANTAGE OF ORGANIC CHEMISTRY? |
Some of the advantages of organic chemistry is given below. To transform the design & synthesis of small molecules to enable interaction with any genomic protein,e.g. expansion of available chemical space th rough synthetic methodologies/technologies,improvement of ‘drug-like’ properties of existing agents. To develop the scientific basis of predictive toxicology,Understanding the interrelationship between drug structure, reactivity, metabolism and toxicology and to develop guidelines for predictive design (cf Lipinski for absorption) To support clinical studies with chemical tools Use of translational chemistry for non-invasive monitoring in vivo(e.g. contrasting agents, biomarkers). To discover the next generation of biological drugs Transform biologics synthesis through integration of small molecule synthetic chemistry with synthetic biology (cf. semi-synthetic natural product synthesis) To develop the scientific basis of drug delivery and selective tissue targeting investigating at a molecular level the chemical basis for transport and distribution of drugs and to develop tools to support predictive design. |